Élise Duchesne

elise duchesne

Working Group Member

Associate Professor, Department of Health Sciences, Université du Québec à Chicoutimi

Researcher, Groupe de recherche interdisciplinaire sur les maladies neuromusculaires (GRIMN)

NMD4C Working Group(s): Biobanking

Email Élise

Research Interests: muscle plasticity, skeletal muscle physiology, macrophage, muscle biology / physiology, cell culture, innate immunity, flow cytometry, cellular immunology, muscle damage

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Dr. Duchesne graduated from Laval University’s physiotherapy program in 2006. Her passion for research led her to undertake a master’s degree followed by a Ph.D. from 2006 to 2012. Her thesis focused on skeletal muscle injuries, more specifically on the contribution of inflammation to the repair process. In January 2012, Dr. Duchesne was hired as a professor/researcher in the Université du Québec à Chicoutimi’s physiotherapy program.

As an independent researcher, her works focus namely on developing rehabilitation interventions. She carried out original and innovative experimental designs based on her knowledge in muscle physiology and her access to the large cohorts of NMD patients found in the Saguenay–Lac-St-Jean region such as myotonic dystrophy type I (DM1).

Her contributions to the field of neuromuscular diseases include the clinical and fundamental study of strength training effects on skeletal muscle impairments, the support of clinical trial readiness by reaching international consensus on outcome measures, the documentation of metrological properties, the documentation natural history of the disease and the establishment of a phenotypic data and biological material biobank.

Recent Publications

Gallais, B, Roussel, MP, Laberge, L, Hébert, LJ, Duchesne, E. Impact of a 12-week Strength Training Program on Fatigue, Daytime Sleepiness, and Apathy in Men with Myotonic Dystrophy Type 1. J Neuromuscul Dis. 2022.9 (5)629-639 PMID:35848033

Ravel-Chapuis, A, Duchesne, E, Jasmin, BJ. Pharmacological and exercise-induced activation of AMPK as emerging therapies for myotonic dystrophy type 1 patients. J Physiol. 2022.600 (14)3249-3264 PMID:35695045

Morin, M, Duchesne, E, Bernier, J, Blanchette, P, Langlois, D, Hébert, LJ et al.. What is Known About Muscle Strength Reference Values for Adults Measured by Hand-Held Dynamometry: A Scoping Review. Arch Rehabil Res Clin Transl. 2022.4 (1)100172 PMID:35282144

Bélair, N, Côté, I, Gagnon, C, Mathieu, J, Duchesne, E. Explanatory factors of dynamic balance impairment in myotonic dystrophy type 1. Muscle Nerve. 2022.65 (6)683-687 PMID:35212003

Roussel, MP, Fiset, MM, Gauthier, L, Lavoie, C, McNicoll, É, Pouliot, L et al.. Assessment of muscular strength and functional capacity in the juvenile and adult myotonic dystrophy type 1 population: a 3-year follow-up study. J Neurol. 2021.268 (11)4221-4237 PMID:33907889

Lessard, I, Gaboury, S, Gagnon, C, Bouchard, K, Chapron, K, Lavoie, M et al.. Effects and Acceptability of an Individualized Home-Based 10-Week Training Program in Adults with Myotonic Dystrophy Type 1. J Neuromuscul Dis. 2021.8 (1)137-149 PMID:33252090

Roussel, MP, Hébert, LJ, Duchesne, E. Strength-training effectively alleviates skeletal muscle impairments in myotonic dystrophy type 1. Neuromuscul Disord. 2020.30 (4)283-293 PMID:32340814

Duchesne, E, Hébert, LJ, Mathieu, J, Côté, I, Roussel, MP, Gagnon, C et al.. Validity of the Mini-BESTest in adults with myotonic dystrophy type 1. Muscle Nerve. 2020.62 (1)95-102 PMID:32314404

Roussel, MP, Morin, M, Girardin, M, Fortin, AM, Leone, M, Mathieu, J et al.. Training program-induced skeletal muscle adaptations in two men with myotonic dystrophy type 1. BMC Res Notes. 2019.12 (1)526 PMID:31429798

Roussel, MP, Hébert, LJ, Duchesne, E. Intra-Rater Reliability and Concurrent Validity of Quantified Muscle Testing for Maximal Knee Extensors Strength in Men with Myotonic Dystrophy Type 1. J Neuromuscul Dis. 2019.6 (2)233-240 PMID:31127731

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