Maria Masnata
Biography
Maria has over 10 years of experience in clinical and in preclinical research in the field of the Neurosciences. She received her M.Sc. in Pharmacy from University of Cagliari in 2015 and her Ph.D. in Neurobiology from Université Laval in 2021. Maria developed extensive experience in clinical research and project management during her previous role as the Assistant Manager of the Investigator-Initiated Trial team of the Clinical Research Unit at The Montreal Neurological Institute/Hospital (McGill University). With a proven track record of managing and coordinating projects leading to Health Canada-approved clinical trials, peer-reviewed publications and national/international presentations, Maria is committed to advancing healthcare and advocating for scientific innovation in her role as Clinical Trials and Community Practice Manager at Muscular Dystrophy Canada.
Recent Publications
Alpaugh, M, Masnata, M, de Rus Jacquet, A, Lepinay, E, Denis, HL, Saint-Pierre, M et al.. Passive immunization against phosphorylated tau improves features of Huntington's disease pathology. Mol Ther. 2022.30 (4)1500-1522 PMID:35051614
Masnata, M, Salem, S, de Rus Jacquet, A, Anwer, M, Cicchetti, F. Targeting Tau to Treat Clinical Features of Huntington's Disease. Front Neurol. 2020.11 580732 PMID:33329322
Rieux, M, Alpaugh, M, Sciacca, G, Saint-Pierre, M, Masnata, M, Denis, HL et al.. Correction: Shedding a new light on Huntington's disease: how blood can both propagate and ameliorate disease pathology. Mol Psychiatry. 2021.26 (9)5464 PMID:32709993
Rieux, M, Alpaugh, M, Sciacca, G, Saint-Pierre, M, Masnata, M, Denis, HL et al.. Shedding a new light on Huntington's disease: how blood can both propagate and ameliorate disease pathology. Mol Psychiatry. 2021.26 (9)5441-5463 PMID:32514103
Maxan, A, Sciacca, G, Alpaugh, M, Tao, Z, Breger, L, Dehay, B et al.. Use of adeno-associated virus-mediated delivery of mutant huntingtin to study the spreading capacity of the protein in mice and non-human primates. Neurobiol Dis. 2020.141 104951 PMID:32439599
Masnata, M, Sciacca, G, Maxan, A, Bousset, L, Denis, HL, Lauruol, F et al.. Demonstration of prion-like properties of mutant huntingtin fibrils in both in vitro and in vivo paradigms. Acta Neuropathol. 2019.137 (6)981-1001 PMID:30788585
Masnata, M, Cicchetti, F. The Evidence for the Spread and Seeding Capacities of the Mutant Huntingtin Protein in in Vitro Systems and Their Therapeutic Implications. Front Neurosci. 2017.11 647 PMID:29234268
Enacán, RE, Masnata, ME, Belforte, F, Papendieck, P, Olcese, MC, Siffo, S et al.. [Transient congenital hypothyroidism due to biallelic defects of DUOX2 gene. Two clinical cases]. Arch Argent Pediatr. 2017.115 (3)e162-e165 PMID:28504502
See more on PubMed