Kessen Patten
Working Group Member
Associate Professor - Centre Armand-Frappier Santé Biotechnologie
Institut National de la Recherche Scientifique (INRS)
NMD4C Involvement: Pillar 1: Preclinical Science, Theme 5: Open Science
Email KessenBiography
Dr. Kessen Patten is an Associate Professor at the INRS-Institut Armand Frappier in Canada. He did his PhD in Physiology and Cell Biology at the University of Alberta, followed by two postdoctoral trainings at the Université de Montreal. During his academic training, Dr. Patten has provided new insights in mechanisms of synaptic development using zebrafish, discovered a new gene associated with idiopathic scoliosis and identified neuroleptics as potential therapeutics for amyotrophic lateral sclerosis (ALS), with one compound currently in clinical trial.
The Patten lab uses the zebrafish to model developmental genetic disorders and neuromuscular diseases (ALS and SMA) to understand disease mechanisms and for drug discovery. Dr. Patten is the recipient of the ALS Canada and Brain Canada Career transition award as well as a Fonds de recherche du Québec – Santé (FRQS) Junior 2 Research Scholar. He also holds the Anna Sforza Djoukhadjian Research Chair in ALS.
Recent Publications
Rajasekharan, S, Barragan Torres, VA, Pinheiro Gomes, YC, Wilken, L, Overhoff, K, Lin, YC et al.. A genus-wide interaction atlas across NS4B orthologues identifies a conserved role for UFMylation in orthoflavivirus replication. Nat Commun. 2026.17 (1) PMID:41826287
Singh, J, Lescouzères, L, Zaouter, C, Chaineau, M, Haghi, G, Durcan, TM et al.. PAICS mediates DNA damage and cerebellar neuronal loss in C9orf72 amyotrophic lateral sclerosis. Brain. 2026. PMID:41810938
Ghosh, S, Singh, J, Damseh, NS, Severino, M, De Pace, R, Golding, AE et al.. EIPR1 variants cause a neurodevelopmental disorder with endolysosomal and dense core vesicle defects. Brain. 2025. PMID:41058046
Chauhan, DS, Zhang, H, Robert, J, Chisanga, M, Rabanel, JM, Mekhjian, D et al.. Bottlebrush Polymer Templates for the Synthesis of Gold Nanostructures and their Applications as Photothermal Agents and SERS Substrates. Small Methods. 2025.9 (11)e01059 PMID:41047541
Gomes, YCP, Sow, AA, Patten, SA, Chatel-Chaix, L. Quantification of Neural Progenitor Cells From Zika Virus-Infected Zebrafish Embryos. Bio Protoc. 2025.15 (13)e5377 PMID:40655417
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