Lawrence Korngut

Dr. Lawrence Korngut

Investigator

Neuromuscular Neurologist, Associate Professor, Department of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary


NMD4C Involvement: Pillar 2: Clinical Research, Theme 5: Open Science

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Biography

Dr. Lawrence Korngut is a neurologist, clinical neurophysiologist and former Director of the Calgary Neuromuscular Program and the Calgary ALS and Motor Neuron Disease Clinic. His research includes phase II and III clinical trials of new therapies for neuromuscular conditions. He is the National Principal Investigator of the Canadian Neuromuscular Disease Registry that now includes 48 participating clinics and over the past ten years has recruited over 5500 patients. 

 

Dr. Korngut completed his undergraduate degree in Life Sciences at Queen’s University (Kingston, Canada), medical school and neurology residency at Western University (London, Canada), neuromuscular clinical and research fellowship and Masters of Science in Clinical Epidemiology at the University of Calgary, Alberta, Canada. He serves as the Director of Innovation and Commercialization at the Hotchkiss Brain Institute. 

 

Within NMD4C Dr. Korngut will bring in his experience of Canadian networking in CAN-NMD and participates in the network’s work in trial capacity building. 


Recent Publications

Dimmick, HL, Jewett, G, Korngut, LW, Ferber, R. Longitudinal relationships between free-living activities, fatigue, and symptom severity in myasthenia gravis using cohort and individualized models. Muscle Nerve. 2025.71 (1)33-42 PMID:39473433

Sharkey, RJ, Cortese, F, Goodyear, BG, Korngut, LW, Jacob, SM, Sharkey, KA et al.. Longitudinal analysis of glymphatic function in amyotrophic lateral sclerosis and primary lateral sclerosis. Brain. 2024.147 (12)4026-4032 PMID:39241118

Beland, B, Perera, T, Lee, A, Greenfield, J, Korngut, L, Jewett, G et al.. No sex-based differences in odds of starting or time to treatment of generalized myasthenia gravis: A single center cohort study. Muscle Nerve. 2024.70 (4)774-781 PMID:39054840

Müller, HP, Abrahao, A, Beaulieu, C, Benatar, M, Dionne, A, Genge, A et al.. Temporal and spatial progression of microstructural cerebral degeneration in ALS: A multicentre longitudinal diffusion tensor imaging study. Neuroimage Clin. 2024.43 103633 PMID:38889523

Parnianpour, P, Benatar, M, Briemberg, H, Dey, A, Dionne, A, Dupré, N et al.. Mismatch between clinically defined classification of ALS stage and the burden of cerebral pathology. J Neurol. 2024.271 (5)2547-2559 PMID:38282082

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