Lawrence Korngut
Investigator
Neuromuscular Neurologist, Professor, Department of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary
NMD4C Involvement: Pillar 2: Clinical Research, Theme 5: Open Science
Email LawrenceBiography
Dr. Lawrence Korngut is a neurologist, clinical neurophysiologist and former Director of the Calgary Neuromuscular Program and the Calgary ALS and Motor Neuron Disease Clinic. His research includes phase II and III clinical trials of new therapies for neuromuscular conditions. He is the National Principal Investigator of the Canadian Neuromuscular Disease Registry that now includes 48 participating clinics and over the past ten years has recruited over 5500 patients.
Dr. Korngut completed his undergraduate degree in Life Sciences at Queen’s University (Kingston, Canada), medical school and neurology residency at Western University (London, Canada), neuromuscular clinical and research fellowship and Masters of Science in Clinical Epidemiology at the University of Calgary, Alberta, Canada. He serves as the Director of Innovation and Commercialization at the Hotchkiss Brain Institute.
Within NMD4C Dr. Korngut will bring in his experience of Canadian networking in CAN-NMD and participates in the network’s work in trial capacity building.
Recent Publications
Smith, IC, Abusetah, Y, Osman, H, Garg, A, Grant, A, Lochmuller, H et al.. Assessing the socio-economic burden of inherited and inflammatory neuromuscular diseases (BIND study): a study protocol. Orphanet J Rare Dis. 2025.20 (1)404 PMID:40770363
Shefner, JM, Cudkowicz, ME, Genge, A, Hardiman, O, Al-Chalabi, A, Andrews, JA et al.. Reldesemtiv in Amyotrophic Lateral Sclerosis: Results From the COURAGE-ALS Randomized Clinical Trial. JAMA Neurol. 2025.82 (5)477-485 PMID:40126464
Lajoie, I, Canadian ALS Neuroimaging Consortium (CALSNIC), Kalra, S, Dadar, M. Regional Cerebral Atrophy Contributes to Personalized Survival Prediction in Amyotrophic Lateral Sclerosis: A Multicentre, Machine Learning, Deformation-Based Morphometry Study. Ann Neurol. 2025.97 (6)1144-1157 PMID:39985309
Peric, S, Ivanovic, V, Ashley, EJ, Esparis, B, Campbell, C, Wenninger, S et al.. International collaboration to improve knowledge on myotonic dystrophy type 2. J Neuromuscul Dis. 2024.11 (6)1229-1237 PMID:39973464
Dimmick, HL, Jewett, G, Korngut, LW, Ferber, R. Longitudinal relationships between free-living activities, fatigue, and symptom severity in myasthenia gravis using cohort and individualized models. Muscle Nerve. 2025.71 (1)33-42 PMID:39473433
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