Lawrence Korngut

Dr. Lawrence Korngut

Investigator

Neuromuscular Neurologist, Professor, Department of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary


NMD4C Involvement: Pillar 2: Clinical Research, Theme 5: Open Science

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Biography

Dr. Lawrence Korngut is a neurologist, clinical neurophysiologist and former Director of the Calgary Neuromuscular Program and the Calgary ALS and Motor Neuron Disease Clinic. His research includes phase II and III clinical trials of new therapies for neuromuscular conditions. He is the National Principal Investigator of the Canadian Neuromuscular Disease Registry that now includes 48 participating clinics and over the past ten years has recruited over 5500 patients. 

 

Dr. Korngut completed his undergraduate degree in Life Sciences at Queen’s University (Kingston, Canada), medical school and neurology residency at Western University (London, Canada), neuromuscular clinical and research fellowship and Masters of Science in Clinical Epidemiology at the University of Calgary, Alberta, Canada. He serves as the Director of Innovation and Commercialization at the Hotchkiss Brain Institute. 

 

Within NMD4C Dr. Korngut will bring in his experience of Canadian networking in CAN-NMD and participates in the network’s work in trial capacity building. 


Recent Publications

Voermans, NC, Statland, JM, Hayward, LJ, Rosenbohm, A, López de Munain, A, Sacconi, S et al.. A randomized, double-blind, placebo-controlled study of losmapimod in patients with facioscapulohumeral muscular dystrophy: Results of the REACH study. J Neuromuscul Dis. 2026. 22143602261419558 PMID:41649965

Schellenberg, KL, Caspar-Bell, G, Ellis, C, Johnston, W, King, A, King, M et al.. [Not Available]. CMAJ. 2026.198 (3)E96-E111 PMID:41587800

Rudnicki, SA, Giacomelli, E, Herder, K, Ingre, C, Kupfer, S, Malik, FI et al.. The Use of Durable Medical Equipment in COURAGE-ALS, a Phase 3, Multicentre, Randomized Clinical Trial for ALS. Muscle Nerve. 2026. PMID:41553108

Jacob, SM, Son, B, Bagheri, S, Lee, S, Leckie, J, Chohan, B et al.. The Oral Microbiome in Amyotrophic Lateral Sclerosis Shows Differentially Abundant Organisms in Limb Versus Bulbar Onset Disease: A Binational Study. J Clin Neurol. 2026.22 (1)66-75 PMID:41517814

Kools, J, Korngut, L, Petrillo Ballantyne, J, Roozen, I, de Haas, R, Hill, A et al.. A toolkit for new facioscapulohumeral muscular dystrophy trial sites. J Neuromuscul Dis. 2025. 22143602251399244 PMID:41451875

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