Jason Karamchandani
Working Group Member
Associate Professor, Department of Pathology, McGill University
Clinical Neuropathologist, Scientific Director of C-BIG Repository, The Montreal Neurological Institute and Hospital, McGill University Health Centre Research Institute
NMD4C Involvement: Pillar 1: Preclinical Science, Theme 5: Open Science
Email JasonBiography
Dr. Jason Karamchandani is an Associate Professor in the Departments of Pathology, Neurology & Neuroscience and is a clinical neuropathologist at The Montreal Neurological Institute and Hospital (the Neuro) where he supports adult and pediatric pathology, including neuromuscular pathology. He serves as the Scientific Director of the Neuro’s Open Science biobank and patient registry, C-BIG.
A graduate of Harvard University, where he received his AB Honours degree in biochemistry cum laude, Dr. Karamchandani earned his medical degree at Stanford University School of Medicine where he was class valedictorian. At Stanford, he pursued residency training in anatomic pathology, as well as fellowship training in surgical pathology and neuropathology. He currently serves as the president of the Canadian Association of Pathology.
Among his scientific achievements, Dr. Karamchandani has authored or co-authored over 80 publications in peer-reviewed journals. He has published four book chapters, with the most recent describing the molecular alterations and clinical tests in tumours of the central nervous system, and tumours of the spinal cord.
Recent Publications
Saunders, N, Magnussen, C, Kang, H, Blais, M, Bhinder, H, Pfeffer, G et al.. Comprehensive analysis platform to understand, remedy, and eliminate amyotrophic lateral sclerosis (CAPTURE ALS): Study protocol for a Canadian multicenter, multimodal, longitudinal observational study. PLoS One. 2025.20 (12)e0332430 PMID:41343582
Shen, HC, Landon-Cardinal, O, Bourré-Tessier, J, Hoa, S, Zarka, F, Nehme, J et al.. Revisiting the link between oropharyngeal dysphagia and cancer in autoimmune myositis: a descriptive study. Arthritis Res Ther. 2025.27 (1)210 PMID:41233913
von Ellenrieder, N, Alrashid, M, Myers, K, Osterman, B, Simard-Tremblay, E, Karamchandani, J et al.. No association between histopathology and neurophysiology in surgical specimens from pediatric focal epilepsy patients. Epilepsia. 2025.66 (9)3168-3179 PMID:40372349
Pekeles, H, Karamchandani, J, Altman, R. [Not Available]. CMAJ. 2025.197 (8)E231-E232 PMID:40032285
Pekeles, H, Karamchandani, J, Altman, R. Colchicine-induced vacuolar myopathy. CMAJ. 2025.197 (3)E69-E70 PMID:39870408
Shahzad, U, Nikolopoulos, M, Li, C, Johnston, M, Wang, JJ, Sabha, N et al.. CASCADES, a novel SOX2 super-enhancer-associated long noncoding RNA, regulates cancer stem cell specification and differentiation in glioblastoma. Mol Oncol. 2025.19 (3)764-784 PMID:39323013
Wiesman, AI, Madge, V, Fon, EA, Dagher, A, Collins, DL, Baillet, S et al.. Associations between neuromelanin depletion and cortical rhythmic activity in Parkinson's disease. Brain. 2025.148 (3)875-885 PMID:39282945
Andrade, AF, Annett, A, Karimi, E, Topouza, DG, Rezanejad, M, Liu, Y et al.. Immune landscape of oncohistone-mutant gliomas reveals diverse myeloid populations and tumor-promoting function. Nat Commun. 2024.15 (1)7769 PMID:39237515
Wang, P, Li, Z, Kim, SH, Xu, H, Huang, H, Yang, C et al.. PPM1G dephosphorylates eIF4E in control of mRNA translation and cell proliferation. Life Sci Alliance. 2024.7 (10) PMID:39111820
da Silva Castanheira, J, Wiesman, AI, Hansen, JY, Misic, B, Baillet, S, PREVENT-AD Research Group et al.. The neurophysiological brain-fingerprint of Parkinson's disease. EBioMedicine. 2024.105 105201 PMID:38908100
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