Rami Massie

Dr. Rami Massie

Co-Applicant

Associate Professor of Neurology at McGill University

Neurologist at the Montreal Neurological Institute and Montreal General Hospital Neuropathy Clinic


NMD4C Involvement: Pillar 2: Clinical Research, Pillar 3: Clinical Practice Research

Email Rami

Research Interests: Peripheral neuropathies, Amyloid polyneuropathy, Nerve biopsies

Academic web profile
ResearchGate profile
ORCiD profile

Biography

Dr. Rami Massie is a neurologist specialized in neuromuscular disorders. His clinical activities consist of seeing patients in the EMG laboratory, in the ALS clinic and in the neuromuscular clinic, with a particular interest in disorders of peripheral nerves. He also works in the Montreal General Hospital Neuropathy Clinic. He collaborates with the peripheral nerve surgeons and the neuropathologists to elucidate etiologies of peripheral neuropathies. 

His area of research is mainly clinical. In addition to participating in clinical drug trials in the fields of ALS and peripheral neuropathies, he supervises fellow and resident research projects in neuromuscular disorders.  


Recent Publications

Shen, HC, Landon-Cardinal, O, Bourré-Tessier, J, Hoa, S, Zarka, F, Nehme, J et al.. Revisiting the link between oropharyngeal dysphagia and cancer in autoimmune myositis: a descriptive study. Arthritis Res Ther. 2025.27 (1)210 PMID:41233913

Bontrager, JE, White, AL, Brigatti, KW, Laxen, W, Loken, PR, Grider, T et al.. Urine Sorbitol and Xylitol for the Diagnosis of Sorbitol Dehydrogenase Deficiency-Related Neuropathy. Neurology. 2025.105 (11)e214425 PMID:41223342

Iruzubieta, P, Pellerin, D, Ashton, C, Villa, F, Renaud, M, Dicaire, MJ et al.. Delineating the pathogenic threshold and phenotypic spectrum of SCA27B: findings from a large French-Canadian cohort. J Neurol. 2025.272 (9)636 PMID:40974444

Saldanha, M, Chen, LK, Solomon, J, Cunanan, K, Tournoux, F, Massie, R et al.. Beyond the Heart: Exploring Extracardiac Manifestations in Cardiac Amyloidosis for Early Diagnosis. Curr Cardiol Rep. 2025.27 (1)105 PMID:40563051

Bril, V, Drużdż, A, Grosskreutz, J, Habib, AA, Kaminski, HJ, Mantegazza, R et al.. Safety and efficacy of chronic weekly rozanolixizumab in generalized myasthenia gravis: the randomized open-label extension MG0004 study. J Neurol. 2025.272 (4)275 PMID:40105996

St-Denis, A, Massie, R. Charcot and recent French cinema. J Hist Neurosci. 2025.34 (2)368-377 PMID:38857470

Benatar, M, Hansen, T, Rom, D, Geist, MA, Blaettler, T, Camu, W et al.. Safety and efficacy of arimoclomol in patients with early amyotrophic lateral sclerosis (ORARIALS-01): a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial. Lancet Neurol. 2024.23 (7)687-699 PMID:38782015

AlSabah, AA, Alsalmi, M, Massie, R, Bilodeau, MC, Campeau, PM, McGraw, S et al.. An adult patient with Tatton-Brown-Rahman syndrome caused by a novel DNMT3A variant and axonal polyneuropathy. Am J Med Genet A. 2024.194 (4)e63484 PMID:38041495

Obici, L, Ajroud-Driss, S, Lin, KP, Berk, JL, Gillmore, JD, Kale, P et al.. Impact of Vutrisiran on Quality of Life and Physical Function in Patients with Hereditary Transthyretin-Mediated Amyloidosis with Polyneuropathy. Neurol Ther. 2023.12 (5)1759-1775 PMID:37523143

Bril, V, Drużdż, A, Grosskreutz, J, Habib, AA, Mantegazza, R, Sacconi, S et al.. Safety and efficacy of rozanolixizumab in patients with generalised myasthenia gravis (MycarinG): a randomised, double-blind, placebo-controlled, adaptive phase 3 study. Lancet Neurol. 2023.22 (5)383-394 PMID:37059507

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