The neuromuscular network for Canada


Hugh McMillan


Clinical Investigator, CHEO Research Institute

Associate Professor, uOttawa Department of Pediatrics,

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Dr Hugh McMillan is an Associate Professor of Pediatrics at the University of Ottawa, a Pediatric Neurologist and Neuromuscular specialist at the Children’s Hospital of Eastern Ontario (CHEO) and a Clinical Investigator at the CHEO Research Institute. His area of clinical expertise is caring for children and youth with inherited and acquired disorders of peripheral nerve, muscle and neuromuscular junction. He follows children in the Neuro-Oncology clinic as well as a General Child Neurology clinic. His research interests include clinical research, clinical trials (investigator-initiated and sponsor-initiated studies) as well as translational research in cooperation with basic scientists. He has been an author or co-author of more than 55 publications in peer-reviewed journals. He recently co-edited a textbook, “Pediatric Electromyography: Concepts and Clinical Applications”. He is active in the community as a Member of the Muscular Dystrophy Canada Scientific Advisory Board and is the Chair of the Canadian Pediatric Neuromuscular Group.

Recent publications

McMillan, HJ, Amid, A, Gonorazky, H, Almobarak, S, Campbell, C. Drisapersen associated with elevated serum factor VIII levels in Duchenne muscular dystrophy. Neurology. 2020. PMID:32075891

Amlie-Lefond, C, Shaw, DWW, Cooper, A, Wainwright, MS, Kirton, A, Felling, RJ et al.. Risk of Intracranial Hemorrhage Following Intravenous tPA (Tissue-Type Plasminogen Activator) for Acute Stroke Is Low in Children. Stroke. 2020.51 (2)542-548 PMID:31842706

Yaworski, AM, McMillan, HJ. Developmental delay and neuropsychiatric comorbidities associated with Duchenne and Becker muscular dystrophy. Muscle Nerve. 2020.61 (2)127-128 PMID:31811661

Kang, PB, McMillan, HJ, Kuntz, NL, Lehky, TJ, Alter, KE, Fitzpatrick, KF et al.. Utility and practice of electrodiagnostic testing in the pediatric population: An AANEM consensus statement. Muscle Nerve. 2020.61 (2)143-155 PMID:31724199

Schubert, RD, Hawes, IA, Ramachandran, PS, Ramesh, A, Crawford, ED, Pak, JE et al.. Pan-viral serology implicates enteroviruses in acute flaccid myelitis. Nat. Med. 2019.25 (11)1748-1752 PMID:31636453

McMillan, HJ. Nusinersen: Evidence of sustained clinical improvement and lessened fatigue in older ambulatory patients with spinal muscular atrophy. Muscle Nerve. 2020.61 (1)1-2 PMID:31599453

Deguise, MO, Baranello, G, Mastella, C, Beauvais, A, Michaud, J, Leone, A et al.. Abnormal fatty acid metabolism is a core component of spinal muscular atrophy. Ann Clin Transl Neurol. 2019.6 (8)1519-1532 PMID:31402618

Gillespie, MK, McMillan, HJ, Kernohan, KD, Pena, IA, Meyer-Schuman, R, Care4Rare Canada Consortium et al.. A Novel Mutation in MARS in a Patient with Charcot-Marie-Tooth Disease, Axonal, Type 2U with Congenital Onset. J Neuromuscul Dis. 2019.6 (3)333-339 PMID:31356216

Ding, JZ, McMillan, HJ. "Owl's Eye" Sign in Acute Flaccid Paralysis. Can J Neurol Sci. 2019.46 (6)756-757 PMID:31352915

Strasser, LE, Orr, SL, McMillan, HJ, Doja, A, Callen, DJA. Pediatric Neurology Workforce in Canada: A 5-Year Update. Can J Neurol Sci. 2019.46 (5)566-574 PMID:31347477

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