The Neuromuscular Disease Network for Canada


Hugh McMillan


Clinical Investigator, CHEO Research Institute

Associate Professor, uOttawa Department of Pediatrics,

Email Hugh

Read more about Hugh


Dr Hugh McMillan is an Associate Professor of Pediatrics at the University of Ottawa, a Pediatric Neurologist and Neuromuscular specialist at the Children’s Hospital of Eastern Ontario (CHEO) and a Clinical Investigator at the CHEO Research Institute. His area of clinical expertise is caring for children and youth with inherited and acquired disorders of peripheral nerve, muscle and neuromuscular junction. He follows children in the Neuro-Oncology clinic as well as a General Child Neurology clinic. His research interests include clinical research, clinical trials (investigator-initiated and sponsor-initiated studies) as well as translational research in cooperation with basic scientists. He has been an author or co-author of more than 55 publications in peer-reviewed journals. He recently co-edited a textbook, “Pediatric Electromyography: Concepts and Clinical Applications”. He is active in the community as a Member of the Muscular Dystrophy Canada Scientific Advisory Board and is the Chair of the Canadian Pediatric Neuromuscular Group.

Recent publications

Kichula, EA, Proud, CM, Farrar, MA, Kwon, JM, Saito, K, Desguerre, I et al.. Expert recommendations and clinical considerations in the use of onasemnogene abeparvovec gene therapy for spinal muscular atrophy. Muscle Nerve. 2021. PMID:34196026

Finkel, RS, McDonald, CM, Lee Sweeney, H, Finanger, E, Neil Knierbein, E, Wagner, KR et al.. A Randomized, Double-Blind, Placebo-Controlled, Global Phase 3 Study of Edasalonexent in Pediatric Patients with Duchenne Muscular Dystrophy: Results of the PolarisDMD Trial. J Neuromuscul Dis. 2021. PMID:34120912

Oskoui, M, Gonorazky, H, McMillan, HJ, Dowling, JJ, Amin, R, Gagnon, C et al.. Guidance on gene replacement therapy in Spinal Muscular Atrophy: a Canadian perspective. Can J Neurol Sci. 2021. 1-11 PMID:34082851

McMillan, HJ, Lochm├╝ller, H. Biomarkers in Duchenne and Becker muscular dystrophies. Muscle Nerve. 2021.64 (1)4-5 PMID:34076279

McMillan, HJ, Gerber, B, Cowling, T, Khuu, W, Mayer, M, Wu, JW et al.. Burden of Spinal Muscular Atrophy (SMA) on Patients and Caregivers in Canada. J Neuromuscul Dis. 2021.8 (4)553-568 PMID:33749617

See more on PubMed