Lawrence Korngut

Dr. Lawrence Korngut


Neuromuscular Neurologist, Associate Professor, Department of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary

NMD4C Involvement: Pillar 2: Clinical Research, Theme 5: Open Science

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Dr. Lawrence Korngut is a neurologist, clinical neurophysiologist and former Director of the Calgary Neuromuscular Program and the Calgary ALS and Motor Neuron Disease Clinic. His research includes phase II and III clinical trials of new therapies for neuromuscular conditions. He is the National Principal Investigator of the Canadian Neuromuscular Disease Registry that now includes 48 participating clinics and over the past ten years has recruited over 5500 patients. 


Dr. Korngut completed his undergraduate degree in Life Sciences at Queen’s University (Kingston, Canada), medical school and neurology residency at Western University (London, Canada), neuromuscular clinical and research fellowship and Masters of Science in Clinical Epidemiology at the University of Calgary, Alberta, Canada. He serves as the Director of Innovation and Commercialization at the Hotchkiss Brain Institute. 


Within NMD4C Dr. Korngut will bring in his experience of Canadian networking in CAN-NMD and participates in the network’s work in trial capacity building. 

Recent Publications

Parnianpour, P, Benatar, M, Briemberg, H, Dey, A, Dionne, A, Dupré, N et al.. Mismatch between clinically defined classification of ALS stage and the burden of cerebral pathology. J Neurol. 2024.271 (5)2547-2559 PMID:38282082

Price, TR, Hodgkinson, V, Westbury, G, Korngut, L, Innes, MA, Marshall, CR et al.. A Study on the Incidence and Prevalence of 5q Spinal Muscular Atrophy in Canada Using Multiple Data Sources. Can J Neurol Sci. 2024. 1-12 PMID:38178730

Kushol, R, Luk, CC, Dey, A, Benatar, M, Briemberg, H, Dionne, A et al.. SF2Former: Amyotrophic lateral sclerosis identification from multi-center MRI data using spatial and frequency fusion transformer. Comput Med Imaging Graph. 2023.108 102279 PMID:37573646

Dey, A, Luk, CC, Ishaque, A, Ta, D, Srivastava, O, Krebs, D et al.. Motor cortex functional connectivity is associated with underlying neurochemistry in ALS. J Neurol Neurosurg Psychiatry. 2023.94 (3)193-200 PMID:36379713

Miller, TM, Cudkowicz, ME, Genge, A, Shaw, PJ, Sobue, G, Bucelli, RC et al.. Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS. N Engl J Med. 2022.387 (12)1099-1110 PMID:36129998

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