Marine Theret

Marine Theret 3x2

Post-Doctoral Fellow, Rossi Lab, University of British Columbia


Email Marine

Research Interests: inflammation, repair, regeneration, fibrosis

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Biography

Dr. Theret graduated from the University of Nantes (France) in 2009 before undertaking a Master degree at Pierre et Marie Curie University in Paris. She then started her PhD in Dr. Benedicte Chazaud’s laboratory at Descartes University and defended in 2015. Under the supervision of Dr. Rémi Mounier, she focused on the role of metabolism on inflammation resolution and muscle stem cell fate.

In 2016 she started her post-doctoral fellowship under the supervision of Dr. Fabio Rossi at the University of British Columbia. She now works on the cellular interactions between tissue resident mesenchymal stromal cells and the inflammatory milieu, which are primordial for skeletal muscle homeostasis, regeneration, and repair. Her research extends beyond the skeletal muscle tissue as it includes other inflammatory chronic diseases such as asthma or multiple sclerosis.


Recent Publications

Kneppers, A, Ben Larbi, S, Theret, M, Saugues, A, Dabadie, C, Gsaier, L et al.. AMPKα2 is a skeletal muscle stem cell intrinsic regulator of myonuclear accretion. iScience. 2023.26 (12)108343 PMID:38077152

Groppa, E, Martini, P, Derakhshan, N, Theret, M, Ritso, M, Tung, LW et al.. Spatial compartmentalization of signaling imparts source-specific functions on secreted factors. Cell Rep. 2023.42 (2)112051 PMID:36729831

Caratti, G, Desgeorges, T, Juban, G, Stifel, U, Fessard, A, Koenen, M et al.. Macrophagic AMPKα1 orchestrates regenerative inflammation induced by glucocorticoids. EMBO Rep. 2023.24 (2)e55363 PMID:36520372

Donen, GS, White, Z, Sauge, E, Ritso, M, Theret, M, Boyd, J et al.. Thermoneutral Housing and a Western Diet Combination Exacerbates Dysferlin-Deficient Muscular Dystrophy. Muscle Nerve. 2022.66 (4)513-522 PMID:35859452

Tehrani, AY, White, Z, Tung, LW, Zhao, RRY, Milad, N, Seidman, MA et al.. Pleiotropic activation of endothelial function by angiotensin II receptor blockers is crucial to their protective anti-vascular remodeling effects. Sci Rep. 2022.12 (1)9771 PMID:35697767

Theret, M, Rempel, L, Hashimoto, J, Ritso, M, Tung, LW, Li, FF et al.. Elevated numbers of infiltrating eosinophils accelerate the progression of Duchenne muscular dystrophy pathology in mdx mice. Development. 2022.149 (8) PMID:35333325

White, Z, Theret, M, Milad, N, Tung, LW, Chen, WW, Sirois, MG et al.. Cholesterol absorption blocker ezetimibe prevents muscle wasting in severe dysferlin-deficient and mdx mice. J Cachexia Sarcopenia Muscle. 2022.13 (1)544-560 PMID:34927367

Soliman, H, Theret, M, Scott, W, Hill, L, Underhill, TM, Hinz, B et al.. Multipotent stromal cells: One name, multiple identities. Cell Stem Cell. 2021.28 (10)1690-1707 PMID:34624231

Theret, M, Saclier, M, Messina, G, Rossi, FMV. Macrophages in Skeletal Muscle Dystrophies, An Entangled Partner. J Neuromuscul Dis. 2022.9 (1)1-23 PMID:34542080

Malakoutian, M, Theret, M, Yamamoto, S, Dehghan-Hamani, I, Lee, M, Street, J et al.. Larger muscle fibers and fiber bundles manifest smaller elastic modulus in paraspinal muscles of rats and humans. Sci Rep. 2021.11 (1)18565 PMID:34535711

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