Rami Massie

Dr. Rami Massie

Co-Applicant

Associate Professor of Neurology at McGill University

Neurologist at the Montreal Neurological Institute and Montreal General Hospital Neuropathy Clinic


NMD4C Involvement: Pillar 2: Clinical Research, Pillar 3: Clinical Practice Research

Email Rami

Research Interests: Peripheral neuropathies, Amyloid polyneuropathy, Nerve biopsies

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Biography

Dr. Rami Massie is a neurologist specialized in neuromuscular disorders. His clinical activities consist of seeing patients in the EMG laboratory, in the ALS clinic and in the neuromuscular clinic, with a particular interest in disorders of peripheral nerves. He also works in the Montreal General Hospital Neuropathy Clinic. He collaborates with the peripheral nerve surgeons and the neuropathologists to elucidate etiologies of peripheral neuropathies. 

His area of research is mainly clinical. In addition to participating in clinical drug trials in the fields of ALS and peripheral neuropathies, he supervises fellow and resident research projects in neuromuscular disorders.  


Recent Publications

AlSabah, AA, Alsalmi, M, Massie, R, Bilodeau, MC, Campeau, PM, McGraw, S et al.. An adult patient with Tatton-Brown-Rahman syndrome caused by a novel DNMT3A variant and axonal polyneuropathy. Am J Med Genet A. 2024.194 (4)e63484 PMID:38041495

Obici, L, Ajroud-Driss, S, Lin, KP, Berk, JL, Gillmore, JD, Kale, P et al.. Impact of Vutrisiran on Quality of Life and Physical Function in Patients with Hereditary Transthyretin-Mediated Amyloidosis with Polyneuropathy. Neurol Ther. 2023.12 (5)1759-1775 PMID:37523143

Bril, V, Drużdż, A, Grosskreutz, J, Habib, AA, Mantegazza, R, Sacconi, S et al.. Safety and efficacy of rozanolixizumab in patients with generalised myasthenia gravis (MycarinG): a randomised, double-blind, placebo-controlled, adaptive phase 3 study. Lancet Neurol. 2023.22 (5)383-394 PMID:37059507

Meyer, A, Troyanov, Y, Korathanakhun, P, Landon-Cardinal, O, Leclair, V, Allard-Chamard, H et al.. Myositis with prominent B cell aggregates may meet classification criteria for sporadic inclusion body myositis. Neuromuscul Disord. 2023.33 (2)169-182 PMID:36649672

Pellerin, D, Danzi, MC, Wilke, C, Renaud, M, Fazal, S, Dicaire, MJ et al.. Deep Intronic FGF14 GAA Repeat Expansion in Late-Onset Cerebellar Ataxia. N Engl J Med. 2023.388 (2)128-141 PMID:36516086

Miller, TM, Cudkowicz, ME, Genge, A, Shaw, PJ, Sobue, G, Bucelli, RC et al.. Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS. N Engl J Med. 2022.387 (12)1099-1110 PMID:36129998

Huang, YT, Giacomini, PS, Massie, R, Venkateswaran, S, Trudelle, AM, Fadda, G et al.. The White Matter Rounds experience: The importance of a multidisciplinary network to accelerate the diagnostic process for adult patients with rare white matter disorders. Front Neurol. 2022.13 928493 PMID:35959404

Mezreani, J, Audet, S, Martin, F, Charbonneau, J, Triassi, V, Bareke, E et al.. Novel homozygous nonsense mutation of MLIP and compensatory alternative splicing. NPJ Genom Med. 2022.7 (1)36 PMID:35672413

Paul, F, Ng, C, Mohamad Sahari, UB, Nafissi, S, Nilipoor, Y, Tavasoli, AR et al.. RABENOSYN separation-of-function mutations uncouple endosomal recycling from lysosomal degradation, causing a distinct Mendelian disorder. Hum Mol Genet. 2022.31 (21)3729-3740 PMID:35652444

Roy, F, Korathanakhun, P, Karamchandani, J, Dubé, BP, Landon-Cardinal, O, Routhier, N et al.. Myositis with prominent B-cell aggregates causing shrinking lung syndrome in systemic lupus erythematosus: a case report. BMC Rheumatol. 2022.6 (1)11 PMID:35168668

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