Tatiana Koike
Postdoctoral Fellow | Dr. Nicolas Dumont Laboratory
CHU Sainte-Justine Research Center, Université de Montréal, Montreal, Canada
NMD4C Involvement: 2nd Place, Signals That Move Us: Image Competition Winner (2026)
Email Tatiana KoikeBiography
Dr. Tatiana Koike is a Postdoctoral Research Fellow in Dr. Nicolas Dumont’s laboratory at the CHU Sainte-Justine Research Center and Université de Montréal. Her research focuses on developing novel therapeutic approaches for myotonic dystrophy type 1 (DM1), with an emphasis on targeting defective muscle stem cells to improve muscle regeneration and function in neuromuscular disorders. She completed her PhD in Morphofunctional Sciences at the University of São Paulo, Brazil, with expertise in regenerative muscle biology, specialized in cell culture, and robust in vivo and in vitro models. Her translational research program in Canada is currently supported by competitive awards from the Neuromuscular Disease Network for Canada (NMD4C) and the Myotonic Dystrophy Foundation (MDF).
Recent Publications
Santos, AR, Gutierrez, RMS, Koike, TE, Conte, TC, Real, CC, Dumont, NA et al.. Skeletal muscle alterations in Marfan syndrome: a systematic review. J Muscle Res Cell Motil. 2025.46 (3)253-272 PMID:40833584
Joshi, AS, Tomaz da Silva, M, Roy, A, Koike, TE, Wu, M, Castillo, MB et al.. The IRE1α/XBP1 signaling axis drives myoblast fusion in adult skeletal muscle. EMBO Rep. 2024.25 (8)3627-3650 PMID:38982191
Tomaz da Silva, M, Joshi, AS, Castillo, MB, Koike, TE, Roy, A, Gunaratne, PH et al.. Fn14 promotes myoblast fusion during regenerative myogenesis. Life Sci Alliance. 2023.6 (12) PMID:37813488
Santos, AR, Koike, TE, Santana, AM, Miranda, NC, Dell Aquila, RA, Silva, TC et al.. Glutamine supplementation accelerates functional recovery of EDL muscles after injury by modulating the expression of S100 calcium-binding proteins. Histochem Cell Biol. 2023.160 (2)135-146 PMID:37179509
Roy, A, Koike, TE, Joshi, AS, Tomaz da Silva, M, Mathukumalli, K, Wu, M et al.. Targeted regulation of TAK1 counteracts dystrophinopathy in a DMD mouse model. JCI Insight. 2023.8 (10) PMID:37071470
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