NMD4C and MDC are pleased to invite you to a CPD-accredited webinar on Charcot-Marie-Tooth (CMT) clinical research updates. This webinar is primarily targeted at Canadian clinicians, academics, and trainees with an interest in neuromuscular disease. This is an independent clinical/academic webinar with no industry sponsorship or influence, and NMD4C and MDC are providing organizational and technical support.

Chair:

• Dr. Jodi Warman-Chardon | Clinician-Scientist, Director of the Ottawa Neuromuscular Centre, The Ottawa Hospital; Associate Scientist, OHRI; Scientist, CHEORI | Associate Professor of Neurology, Co-Director of the Centre for Neuromuscular Disease, University of Ottawa

Speakers & Agenda:

Update on CANVAS and RFC-1 related neuropathies

• Dr. Rami Massie | Associate Professor of Neurology at McGill University | Neurologist at the Montreal Neurological Institute and Montreal General Hospital Neuropathy Clinic

CMT-SORD – from gene identification to clinical trial

• Dr. Michael Shy | Professor of Neurology, Pediatrics, and Molecular Physiology and Biophysics at University of Iowa | Director, Division of Neuromuscular Medicine, Neurology at University of Iowa Health Care

Learning Objectives:

1. Review the initial description of RFC-1 related disorders and their clinical phenotype.
2. Discuss the expanding phenotype of RFC-1 mutations.
3. Review phenotype-genotype correlation.
4. To identify the clinical phenotype of SORD.
5. To promote awareness of the power of next generation sequencing in rare disorders.
6. To demonstrate the role of biomarkers in diagnosing CMT-SORD.
7. To create awareness of clinical outcome assessments available in inherited neuropathies.

The NMD Rounds & Educational Webinars is a self-approved group learning activity (Section 1) as defined by the Maintenance of Certification Program of the Royal College of Physicians and Surgeons of Canada.